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1

Structure and Function in Rhodopsin. 7. Point Mutations Associated with Autosomal Dominant Retinitis Pigmentosa

Kaushal, Shalesh, Khorana, H. Gobind

Journal:

Year:

1994

Language:

english

File:

PDF, 1.97 MB

english, 1994

2

Structure and Function in Rhodopsin: Packing of the Helices in the Transmembrane Domain and Folding to a Tertiary Structure in the Intradiscal Domain are Coupled

John Hwa, Pere Garriga, Xun Liu and H. Gobind Khorana

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.22 MB

english, 1997

3

Synthesis and structural analysis of polynucleotides

H. Gobind Khorana

Journal:

Journal of Cellular Physiology

Year:

1959

Language:

english

File:

PDF, 887 KB

english, 1959

4

Studies on nucleic acids: Total synthesis of a biologically functional gene

H.Gobind Khorana

Journal:

Bioorganic Chemistry

Year:

1978

Language:

english

File:

PDF, 2.97 MB

english, 1978

5

Vibrational spectroscopy of bacteriorhodopsin mutants: I. Tyrosine-185 protonates and deprotonantes during the photocycle

Mark S. Braiman, Tatsushi Mogi, Lawrence J. Stern, Neil R. Hackett, Betty H. Chao, H. Gobind Khorana, Dr. Kenneth J. Rothschild

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1988

Language:

english

File:

PDF, 1.15 MB

english, 1988

6

Structure and thermal stability of monomeric bacteriorhodopsin in mixed pospholipid/detergent micelles

Christie G. Brouillette, Ruth B. McMichens, Lawrence J. Stern, H. Gobind Khorana

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1989

Language:

english

File:

PDF, 896 KB

english, 1989

7

Combined solid state and solution NMR studies of α,ɛ-15N labeled bovine rhodopsin

Karla Werner, Ines Lehner, Harpreet Kaur Dhiman, Christian Richter, Clemens Glaubitz, Harald Schwalbe, Judith Klein-Seetharaman, H. Gobind Khorana

Journal:

Journal of Biomolecular NMR

Year:

2007

Language:

english

File:

PDF, 365 KB

english, 2007

8

Site directed spin labeling studies of structure and dynamics in bacteriorhodopsin

Heinz-Jürgen Steinhoff, Ramin Mollaaghababa, Christian Altenbach, H. Gobind Khorana, Wayne L. Hubbell

Journal:

Biophysical Chemistry

Year:

1995

Language:

english

File:

PDF, 571 KB

english, 1995

9

Intermediates in the folding of the membrane protein bacteriorhodopsin

Booth, Paula J., Flitsch, Sabine L., Stern, Lawrence J., Greenhalgh, Duncan A., Kim, Peter S., Khorana, H. Gobind

Journal:

Natural Structural Biology

Year:

1995

File:

PDF, 419 KB

1995

10

Site-directed isotope labelling and FTIR spectroscopy of bacteriorhodopsin

Sonar, Sanjay, Lee, Chan-Ping, Coleman, Matthew, Patel, Nilam, Liu, Xiaomei, Marti, Thomas, Khorana, H. Gobind, RajBhandary, Uttam L., Rothschild, Kenneth J.

Journal:

Natural Structural Biology

Year:

1994

File:

PDF, 946 KB

1994

11

A Reminiscence

H. Gobind Khorana

Journal:

Origins of Life and Evolution of Biospheres

Year:

1997

Language:

english

File:

PDF, 27 KB

english, 1997

12

Dipolar assisted rotational resonance NMR of tryptophan and tyrosine in rhodopsin

Evan Crocker, Ashish B. Patel, Markus Eilers, Shobini Jayaraman, Elena Getmanova, Philip J. Reeves, Martine Ziliox, H. Gobind Khorana, Mordechai Sheves, Steven O. Smith

Journal:

Journal of Biomolecular NMR

Year:

2004

Language:

english

File:

PDF, 234 KB

english, 2004

13

The synthesis and high-level expression of a β2-adrenergic receptor gene in a tetracycline-inducible stable mammalian cell line

Prashen Chelikani, Philip J. Reeves, Uttam L. Rajbhandary, H. Gobind Khorana

Journal:

Protein Science

Year:

2006

Language:

english

File:

PDF, 227 KB

english, 2006

14

Fatty acids containing photoactivable carbene precursors. Synthesis and photochemical properties of 3,3-bis(1,1-difluorohexyl)diazirine and 3-(1,1-difluorooctyl)-3H-diazirine

Erni, Bernhard, Khorana, H. Gobind

Journal:

Journal of the American Chemical Society

Year:

1980

Language:

english

File:

PDF, 1.17 MB

english, 1980

15

TIME-RESOLVED FOURIER TRANSFORM INFRARED SPECTROSCOPY OF THE BACTERIORHODOPSIN MUTANT TYR-185→E: ASP-96 REPROTONATES DURING O FORMATION; ASP-85 AND ASP-212 DEPROTONATE DURING O DECAY

Olaf Bousché, Sanjay Sonar, Mark P. Krebs, H. Gobind Khorana, Kenneth J. Rothschild

Journal:

Photochemistry and Photobiology

Year:

1992

Language:

english

File:

PDF, 1.01 MB

english, 1992

16

EFFECTS OF MUTAGENETIC SUBSTITUTION OF PROLINES ON THE RATE OF DEPROTONATION and REPROTONATION OF THE SCHIFF BASE DURING THE PHOTOCYCLE OF BACTERIORHODOPSIN

Yi N. Zhang, Mostafa A. El-Sayed, Lawrence J. Stern, Thomas Marti, Tatushi Mogi, H. Gobind Khorana

Journal:

Photochemistry and Photobiology

Year:

1993

Language:

english

File:

PDF, 556 KB

english, 1993

17

Identification of the Lipid-Binding Site of Phosphatidylcholine-Transfer Protein with Phosphatidylcholine Analogs Containing Photactivable Carbene Precursors

Jan WESTERMAN, Karel W. A. WIRTZ, Theo BERKHOUT, Laurens L. M. VAN DEENEN, Ramachandran RADHAKRISHNAN, H. Gobind KHORANA

Journal:

Year:

1983

Language:

english

File:

PDF, 998 KB

english, 1983

18

Structure and function in bacteriorhodopsin: the role of the interhelical loops in the folding and stability of bacteriorhodopsin

Jong-Myoung Kim, Paula J Booth, Samantha J Allen, H.Gobind Khorana

Journal:

Journal of Molecular Biology

Year:

2001

Language:

english

File:

PDF, 288 KB

english, 2001

19

Structure and function in bacteriorhodopsin: the effect of the interhelical loops on the protein folding kinetics

Samantha J Allen, Jong-Myoung Kim, H.Gobind Khorana, Hui Lu, Paula J Booth

Journal:

Journal of Molecular Biology

Year:

2001

Language:

english

File:

PDF, 311 KB

english, 2001

20

The preparation of lipid-depleted bacteriorhodopsin

Dieter Wildenauer, H.Gobind Khorana

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1977

Language:

english

File:

PDF, 934 KB

english, 1977

21

Interaction of cholesterol with photoactivable phospholipids in sonicated vesicles

Gerhard E. Gerber, Ramachandran Radhakrishhnan, Chhitar M. Gupta, H.Gobind Khorana

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1981

Language:

english

File:

PDF, 626 KB

english, 1981

22

Synthesis of phospholipids containing photoactivatable carbene precursors in the headgroups and their crosslinking with membrane proteins

Bruce K. Burnett, Robert J. Robson, Yohtaroh Takagaki, Ramachandran Radhakrishnan, H.Gobind Khorana

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1985

Language:

english

File:

PDF, 847 KB

english, 1985

23

A rapid and efficient procedure for the purification of mitochondrial β-hydroxybutyrate dehydrogenase

Bruce K. Burnett, H.Gobind Khorana

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1985

Language:

english

File:

PDF, 538 KB

english, 1985

24

Sensitivity of the retinal circular dichroism of bacteriorhodopsin to the mutagenetic single substitution of amino acids: tyrosine

Du-Jeon-Jang, M.A. El-Sayed, Lawrence J. Stern, Tatsushi Mogi, H. Gobind Khorana

Journal:

Year:

1990

Language:

english

File:

PDF, 418 KB

english, 1990

25

The use of tryptophan mutants in identifying the 296 nm transient absorbing species during the photocycle of bacteriorhodopsin

Shuguang Wu, Du-Jeon Jang, M.A. El-Sayed, Thomas Marti, Tatsushi Mogi, H.Gobind Khorana

Journal:

Year:

1991

Language:

english

File:

PDF, 637 KB

english, 1991

26

Changes in Interhelical Hydrogen Bonding upon Rhodopsin Activation

Ashish B. Patel, Evan Crocker, Philip J. Reeves, Elena V. Getmanova, Markus Eilers, H. Gobind Khorana, Steven O. Smith

Journal:

Journal of Molecular Biology

Year:

2005

Language:

english

File:

PDF, 348 KB

english, 2005

27

Opsin Stability and Folding: Modulation by Phospholipid Bicelles

Craig McKibbin, Nicola A. Farmer, Chris Jeans, Philip J. Reeves, H. Gobind Khorana, B.A. Wallace, Patricia C. Edwards, Claudio Villa, Paula J. Booth

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 628 KB

english, 2007

28

Opsin Stability and Folding: The Role of Cys185 and Abnormal Disulfide Bond Formation in the Intradiscal Domain

Craig McKibbin, Ashley M. Toye, Philip J. Reeves, H. Gobind Khorana, Patricia C. Edwards, Claudio Villa, Paula J. Booth

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 720 KB

english, 2007

29

Thiols and the diazo group in photoaffinity labels

Yohtaroh Takagaki, Chhitar M. Gupta, H.Gobind Khorana

Journal:

Biochemical and Biophysical Research Communications

Year:

1980

Language:

english

File:

PDF, 572 KB

english, 1980

30

Rhodopsin, the Visual Pigment, and Bacteriorhodopsin

H. GOBIND KHORANA

Journal:

Annals of the New York Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 723 KB

english, 1986

31

A new photo-crosslinking reagent for the study of protein-protein interactions

Resek, John F., Bhattacharya, Santanu, Khorana, H. Gobind

Journal:

Journal of Organic Chemistry

Year:

1993

Language:

english

File:

PDF, 973 KB

english, 1993

32

Structural studies on transmembrane proteins. 2. Spin labeling of bacteriorhodopsin mutants at unique cysteines

Altenbach, Christian, Flitsch, Sabine L., Khorana, H. Gobind, Hubbell, Wayne L.

Journal:

Year:

1989

Language:

english

File:

PDF, 855 KB

english, 1989

33

[Part 2: Biological Sciences] || Bacteriorhodopsin: Partial Sequence of mRNA Provides Amino Acid Sequence in the Precursor Region

Simon H. Chang, Alokes Majumdar, Robert Dunn, Osamu Makabe, Uttam L. RajBhandary, H. Gobind Khorana, Eiko Ohtsuka, Toshiki Tanaka, Yoshihide O. Taniyama and Morio Ikehara

Journal:

Proceedings of the National Academy of Sciences

Year:

1981

Language:

english

File:

PDF, 1.62 MB

english, 1981

34

[Part 2: Biological Sciences] || The Bacteriorhodopsin Gene

Robert Dunn, John McCoy, Mehmet Simsek, Alokes Majumdar, Simon H. Chang, Uttam L. RajBhandary and H. Gobind Khorana

Journal:

Proceedings of the National Academy of Sciences

Year:

1981

Language:

english

File:

PDF, 1.27 MB

english, 1981

35

[Part 1: Biological Sciences] || A Transposable Element from Halobacterium halobium Which Inactivates the Bacteriorhodopsin Gene

Mehmet Simsek, Shiladitya DasSarma, Uttam L. RajBhandary and H. Gobind Khorana

Journal:

Proceedings of the National Academy of Sciences

Year:

1982

Language:

english

File:

PDF, 1.55 MB

english, 1982

36

[Part 1: Biological Sciences] || High-Frequency Spontaneous Mutation in the Bacterio-Opsin Gene in Halobacterium halobium is Mediated by Transposable Elements

Shiladitya DasSarma, Uttam L. RajBhandary and H. Gobind Khorana

Journal:

Proceedings of the National Academy of Sciences

Year:

1983

Language:

english

File:

PDF, 1.63 MB

english, 1983

37

[Part 1: Biological Sciences] || Bacterio-Opsin mRNA in Wild-Type and Bacterio-Opsin-Deficient Halobacterium halobium Strains

Shiladitya DasSarma, Uttam L. RajBhandary and H. Gobind Khorana

Journal:

Proceedings of the National Academy of Sciences

Year:

1984

Language:

english

File:

PDF, 1.33 MB

english, 1984

38

[Part 1: Biological Sciences] || Specific Amino Acid Substitutions in Bacterioopsin: Replacement of a Restriction Fragment in the Structural Gene by Synthetic DNA Fragments Containing Altered Codons

Kin-Ming Lo, Simon S. Jones, Neil R. Hackett and H. Gobind Khorana

Journal:

Proceedings of the National Academy of Sciences

Year:

1984

Language:

english

File:

PDF, 1.71 MB

english, 1984

39

GTPase of Bovine Rod Outer Segments: The Amino Acid Sequence of the α Subunit as Derived from the cDNA Sequence

Kimio Yatsunami and H. Gobind Khorana

Journal:

Proceedings of the National Academy of Sciences

Year:

1985

Language:

english

File:

PDF, 1.14 MB

english, 1985

40

Total Synthesis of a Gene for Bovine Rhodopsin

Luca Ferretti, Sadashiva S. Karnik, H. Gobind Khorana, Michael Nassal and Daniel D. Oprian

Journal:

Proceedings of the National Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 1.20 MB

english, 1986

41

Bacteriorhodopsin Mutants Containing Single Tyrosine to Phenylalanine Substitutions are All Active in Proton Translocation

Tatsushi Mogi, Lawrence J. Stern, Neil R. Hackett and H. Gobind Khorana

Journal:

Proceedings of the National Academy of Sciences

Year:

1987

Language:

english

File:

PDF, 916 KB

english, 1987

42

Expression of a Synthetic Bovine Rhodopsin Gene in Monkey Kidney Cells

Daniel D. Oprian, Robert S. Molday, Randal J. Kaufman and H. Gobind Khorana

Journal:

Proceedings of the National Academy of Sciences

Year:

1987

Language:

english

File:

PDF, 1.17 MB

english, 1987

43

Aspartic Acid Substitutions Affect Proton Translocation by Bacteriorhodopsin

Tatsushi Mogi, Lawrence J. Stern, Thomas Marti, Betty H. Chao and H. Gobind Khorana

Journal:

Proceedings of the National Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 835 KB

english, 1988

44

Expression of a Bovine Rhodopsin Gene in Xenopus Oocytes: Demonstration of Light-Dependent Ionic Currents

H. Gobind Khorana, Barry E. Knox, Enrico Nasi, Richard Swanson and Debra A. Thompson

Journal:

Proceedings of the National Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 969 KB

english, 1988

45

Cysteine Residues 110 and 187 are Essential for the Formation of Correct Structure in Bovine Rhodopsin

Sadashiva S. Karnik, Thomas P. Sakmar, Hai-Bao Chen and H. Gobind Khorana

Journal:

Proceedings of the National Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 1.07 MB

english, 1988

46

Replacement of Aspartic Residues 85, 96, 115, or 212 Affects the Quantum Yield and Kinetics of Proton Release and Uptake by Bacteriorhodopsin

Tim Marinetti, Sriram Subramaniam, Tatsushi Mogi, Thomas Marti and H. Gobind Khorana

Journal:

Proceedings of the National Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 896 KB

english, 1989

47

Replacement of Aspartic Acid-96 by Asparagine in Bacteriorhodopsin Slows Both the Decay of the M Intermediate and the Associated Proton Movement

Martin Holz, Lel A. Drachev, Tatsushi Mogi, Harald Otto, Andrey D. Kaulen, Maarten P. Heyn, Vladimir P. Skulachev and H. Gobind Khorana

Journal:

Proceedings of the National Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 874 KB

english, 1989

48

Aspartic Acid-96 is the Internal Proton Donor in the Reprotonation of the Schiff Base of Bacteriorhodopsin

Harald Otto, Thomas Marti, Martin Holz, Tatsushi Mogi, Manfred Lindau, H. Gobind Khorana and Maarten P. Heyn

Journal:

Proceedings of the National Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 1.02 MB

english, 1989

49

Structure and Function in Rhodopsin: Correct Folding and Misfolding in Two Point Mutants in the Intradiscal Domain of Rhodopsin Identified in Retinitis Pigmentosa

Xun Liu, Pere Garriga and H. Gobind Khorana

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.05 MB

english, 1996

50

Structure and Function in Rhodopsin: Expression of Functional Mammalian Opsin in Saccharomyces cerevisiae

Ramin Mollaaghababa, Florence F. Davidson, Chris Kaiser and H. Gobind Khorana

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.23 MB

english, 1996